NAB2–STAT6 fusion types account for clinicopathological variations in solitary fibrous tumors
نویسندگان
چکیده
منابع مشابه
The clinicopathological significance of NAB2‐STAT6 gene fusions in 52 cases of intrathoracic solitary fibrous tumors
NAB2-STAT6 gene fusion drives STAT6 nuclear expression and is the pathognomonic hallmark of solitary fibrous tumors (SFTs). However, no study has systematically analyzed the clinicopathological features, STAT6 immunoexpression status, or the fusion variants of NAB2-STAT6 in intrathoracic SFTs. Fifty-two intrathoracic SFTs were retrieved to appraise histopathology, assess STAT6 immunoexpression,...
متن کاملClinicopathological findings in a case series of abdominopelvic solitary fibrous tumors
Solitary fibrous tumors (SFTs) represent a rare type of soft tissue tumor. Extrathoracic SFTs (ESFTs) in the soft tissues of the abdominopelvic cavity are extremely rare. Between January 2002 and January 2013, 10 patients were identified with abdominopelvic SFTs at the Northern Jiangsu People's Hospital. The clinicopathological data, treatment and follow-up results were retrospectively analyzed...
متن کاملClinicopathological findings in a case series of extrathoracic solitary fibrous tumors of soft tissues
BACKGROUND Solitary fibrous tumors (SFT) represent a rare entity of soft tissue tumors. Previously considered being of serosal origin and solely limited to the pleural cavity the tumor has been described in other locations, most particularly the head and neck. Extrathoracic SFT in the soft tissues of the trunk and the extremities are very rare. Nine cases of this rare tumor entity are described...
متن کامل[Clinicopathological features of solitary fibrous tumors of the pleura: a case series and literature review].
We assessed the clinicopathological features of solitary fibrous tumors of the pleura in a case series comprising 30 patients (20 women, 66.6%) with a mean age of 58.39 years. Forty-five percent of the cases were asymptomatic. In 70% of the cases the tumors arose in the visceral pleura. Twenty percent presented multiple tumors, a finding that was associated with intrapulmonary localization and ...
متن کاملSolitary fibrous tumors of the pleura.
PURPOSE OF REVIEW Solitary fibrous tumor of the pleura (SFTP) is a rare neoplasm of the pleura. Although an increasing number of case series have been reported in recent years, so far clinical behavior is still unpredictable. The following article presents a detailed review of the recent larger series of SFTP with particular attention to the clinical presentation, pathologic characteristics and...
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ژورنال
عنوان ژورنال: Modern Pathology
سال: 2015
ISSN: 0893-3952,1530-0285
DOI: 10.1038/modpathol.2015.90